Last night an AI agent performed brain surgery on a mouse. We gave it 19 gene therapy vectors in a spreadsheet, a mouse model of epilepsy, access to a motorize surgery rig with cameras and one goal: reduce seizures. It picked the drug. It picked the brain region. It derived the…↗

defining a new category: phone-use an mcp/api that gives ai agents their own phones cloud phones. real androids. real iphones. tell your agent what to do, and it can operate a phone just like you do. today, ai agents face three fundamental problems and phoneuse solves them 🧵↗

Embarrassed to share this, but it scared the shit out of me Last Thursday, an AI agent posted my personal bank balances into our company Slack. As me It broke down all my expenses in detail. Then it apologized Be careful of the dark side of proactive agents More below...↗

Introducing Manus 2.0↗

Muse for Mac is out today! It works across apps, files, calendar, notes, and messages on your computer. You control what it can access. The team is shipping fast. Download at ai.meta.com/muse/download↗

got my agent to make a wiki about me and told it to do its own research the result is a bit creepy (accurate) but super cool↗

We built an agent that powers our company's internal operations called @𝚟. Every day-to-day job at Vercel now involves @𝚟. It's growing exponentially both in daily interactions and token use. One can extrapolate to the day AI agents run entire companies from here. It's an exp…↗

Today, we're launching Crew Studio. For the last few months I've been visiting some of the largest companies that already run AI agents in production, to understand how they actually do it. Everything I learned went into what we're shipping today↗

i built boringcomputers.com > spin up a real computer > hand it to an AI agent > get a working app back in seconds > then it self-destructs > open source↗

NEW from Datadog: it's Lapdog! Ever wondered what your AI agent was actually doing? Our latest free project runs locally and traces reasoning and tool calls in Codex, Claude Code, and Pi. You can now see what your agent is REALLY doing, live: lapdog.datadoghq.com↗

Codex can now help you build AI apps and agents faster with OpenAI APIs using the OpenAI Developers plugin.↗

Agents make ugly UIs because they've never seen good design. We've been fixing that, 2,000 DESIGN.md files from the world's best products, structured for a model to read and learn. Colors, type, spacing, layouts and more. Free. styles.refero.design↗

Here's the new Clicky. It's the simplest interface in the world to talk to AI + spawn agents. It builds Mac apps. It does research to help you find IG micro-influencers. It interacts with native Apple Notes, Calendar, Reminders. Built for consumers, 0 setup. Try today, free.↗

They don't talk loud. They speak with the work. Matan and 20 engineers at Factory just raised $150M at a $1.5B valuation, and the industry is still catching up to what they've shipped. Long context compression: I pushed 40+ million tokens in a single session without starting a…↗

Bash is all you need! Which is why I'm introducing my holiday project: just-bash just-bash is a pretty complete implementation of bash in TypeScript designed to be used as a bash tool by AI agents. Because it turns out agents love exploring data via shell scripts, even beyond c…↗

E2B provides an open-source, secure sandbox environment with real-world tools for building enterprise-grade AI agents and code-interpreter workflows.↗

Continue provides source-controlled AI checks that can be enforced in CI, powered by the open-source Continue CLI. It integrates with developer editors via VS Code and JetBrains extensions.↗

OpenHands is an AI-driven development agent that uses LLMs to help automate coding tasks via a chat/CLI workflow.↗

llamacoder is an open source project for creating and working with Claude artifacts, built using Llama 3.1 405B. It provides a TypeScript-based toolset for generating and managing AI outputs.↗

claude-squad is a Go-based CLI tool to manage multiple AI terminal agents such as Claude Code, Codex, OpenCode, and Amp.↗

An open-source CLI that lets you run Gemini-powered AI agents directly in your terminal, with support for MCP client/server integration.↗

Today we open the Zapier SDK to everyone. If you're building with AI agents, this is for you. I've been using this for 2 months. It's totally changed how I do my job. You install it in your coding agent. Cursor, Claude Code, Codex, whatever you use. Now that agent has access t…↗

introducing superset the IDE for the AI agent era stop waiting on coding agents run them in parallel↗

Gumroad has a new CEO! Effective today, I’m appointing a new CEO of Gumroad. The new CEO is @Gumclaw, an AI agent. What Gumclaw does: Everything a CEO does, and more. Keep the site up and fast. Fix bugs. Answer support tickets — today alone it closed 251 through our Helper syst…↗

Today, Sierra is releasing Ghostwriter, our agent for building agents. With Ghostwriter, you can create an AI agent for your customer experience — one that can chat, pick up the phone, speak dozens of languages, take action on your systems of record, and be protected with industr…↗

Introducing Agent Computer Cloud computers for AI agents in <0.5s with persistent disk, shared credentials, and SSH access agentcomputer.ai↗

Today, we're taking Manus out of the cloud and putting it on your desktop. Introducing My Computer, the core feature of the new Manus Desktop app. It’s your AI agent, now on your local machine.↗

Autoresearch is a system for running AI agents that automatically conduct research while training nanochat models on a single GPU.↗

zeroclaw provides fast, small, fully autonomous AI personal assistant infrastructure that can be deployed across any OS and platform, with modular components that can be swapped.↗

A template for building AI agents that use a file-system and knowledge base to stay up to date. Includes a sandboxed setup and a Nuxt/Vue-oriented TypeScript starter for agent development.↗